Assisted Reproduction Technologies

This includes a number of special technique which assist infertile couples to have children. Some prominent technique are :-

  1. Test tube baby programme
  2. Gamete intra fallopian tube (GIFT)
  3. Intra cytoplasmic sperm injection (ICSI)
  4. Artificial insemination technique (AIT)

Test tube baby programme :- this method involves in vitro fertilization (IVF) , fertilization of male gamete and female gamete outside the body in almost similar conditions as that in the body followed by zygote Or embryo transfer.

In some women normal conception is not possible because of blocked oviducts Or spermicidal secretions in the vagina pr low sperm count of the males. These are also cases wherein women cannot produce ova or men can’t produce sperm. In such cases, ovum from females is remove surgically after hormonal stimulation of the follicle. It is then fertilized by her donor male sperm in am laboratory dish containing a nutrient broth. The zygote up to eight blastomers is then transferred into fallopian tube or embryo with more than eight blastomers is transferred into the uterus.

The entire operations is carried out under the sterilised conditions.

The baby produced by conceiving in culture dish and nursing in the uterus is called a test tube baby. A scientific term for this procedure is In vitro fertilization.

Success rate of test tube babies :- The success rate of the technique of producing test tube baby is less than 20% . To increase the chance of success, the prospective mother given fertility drug which cause many ovarian follicle to mature at same time. This release many eggs simultaneously, there by increasing the chance of success. The additional embryo are transferred to surrogate mother for competition of development. They can also be frozen for later use.

Surrogate mother : a developing embryo can be inserted in the uterus of another female, provided her hormone are in the proper phases of reproductive cycle for implantation to occur. A woman who substitute or take place of the real mother to nurse the embryo is called as surrogate mother.

Problem in producing test tube baby : the production of test tube baby involving the surrogate mother raises some ethical and legal problem such as right over child.

U. S. Government has proposed the following guidelines :-

  1. No embryo should be left outside the mother.
  2. Only married person should contribute egg and sperm for producing test tube baby.
  3. Cost of embryo transplants in surrogate mother will not be funded by the Federal Government
  1. Gamete Intra Fallopian Transfer (GIFT) :- this method is used in female who can’t produce ova but can provide suitable environment for fertilization and further development of embryo in the oviduct. In such case, ovum from the donor female is surgically removed and is them introduced into the Fallopian tube of such female. Such women then accept sperm from male during copulation.
  1. Intra Cytoplasmic Sperm Injection (ICSI) :- it is another specialized technique to form an embryo in the laboratory in which a sperm is directly injected into the ovum placed in a nutrient broth.
  2. Artificial insemination technique (AIT) :- this technique is used in those female where the husband either is unable to insemination the female or has very low sperm count in the ejaculates. In such case, the semen of the husband is first collected and then is artificial introduced either into the vagina or into the uterus of the female.

All the above mentioned technique require extremely high precision handling by specialized professional and expensive instrumentation.

Such facilities are presently available in all IVF centre.. This may lead to complications such as pelvic inflammatory disease PID, abortion, still birth, ectopic pregnancy, infertility or even cancer of the reproductive tract. Sexually transmitted diseases STD are a major threat to a healthy society Under such programmes., Adolescence are specially targeted to follow some principles given below :

  1. Avoid sex with unknown partner or multiple partner
  2. Always use condoms during coitus
  3. If you doubt for an reproductive infection.., go to doctor immediately.

Are you looking for the best IVF center for infertility treatment in MP according to your budget, then you should visit Mohak Infertility Center in Indore, as Mohak Infertility Center is one of the best IVF Centers in Indore. Mohak Infertility Center is  considered very famous for childless couples for many years, because 97% satisfied infertility patients go back to this hospital. We have a very experienced IVF specialist Dr. Shilpa Bhandari. She is an expert in IVF, IUI, test tube baby,  infertility treatment and ICSI treatment. If you are looking for the best center for IVF in Indore, then book an appointment today with infertility treatment hospital in Indore call  us 7898047572.

Request an Appointment / General Inquiry:- https://www.mohakivf.com/Contact-us.htm

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To More Post :- Embryo freezing: What you need to know

SEMEN FREEZING

Semen freezing is the procedure whereby spermatozoa are exposed to cryoprotectants and then cooling them to subzero temperature using liquid nitrogen. Frozen semen samples can be stored for many years while maintaining reasonable parameters of semen. Semen freezing helps in storage, supply or reserve of the human sperm for future use.

Sperm freezing is widely used and established method in humans and other species, it is very effective in Assisted Reproductive technology (ART) and fertility preservation in patients with cancer, before initiation of radiotherapy or chemotherapy. Semen freezing can be done by two methods 1. Noncontrolled rate cryopreservation and 2. Controlled rate cryopreservation.

CLINICAL APPLICATION OF SPERM FREEZING :-

1.Assisted Reproductive Technologies (ART)

2. Fertility Preservation with Cancer Therapy

3. Non- malignancy systemic diseases and other conditions

4. Surgical procedures involving male genitalia

5. Social and other reasons

ART – Assisted reproductive technologies – IUI/IVF/ICSI:

In ART, the most common use of sperm freezing is in artificial insemination, in vitro fertilization (IVF), or intra cytoplasmic sperm injections (ICSI) for various infertile couples. One of the ART options usually offered to infertile couples is intrauterine insemination using fresh or frozen sperm. Although the technique is used preferably with a fresh semen sample, the availability of freezing sperm samples is an option usually offered by infertility clinics in case the male partner cannot produce semen. In case of severe male factor infertility, the samples can be frozen for later use.

Fertility Preservation with Cancer Therapy:

Another application of sperm freezing is for cancer patients before initiation of cancer therapy. The option of sperm freezing should be offered to any male undergoing chemotherapy or radiotherapy as these treatments can have long-term or permanent cytotoxic side effects on testicular function. One of the advantages of semen freezing is here is that the frozen sperm can stand multiple freezing thawing cycles with no effect on the sperm quality; this is beneficial in cases where patients might have testicular cancer and require surgical removal of the whole testis, with no future possibility of obtaining sperm again. For young males before puberty , cryopreservation of testicular tissue may be an option for fertility preservation in future, improved chemotherapy regimens may give hope to patients in terms of maintaining their sexual and fertility potential after therapy, but at present all male patients diagnosed with cancer who wish to have children should consider sperm freezing or cryopreservation of testicular tissues for further ART use.

Non- malignancy systemic diseases and other conditions:

Cryopreservation of sperm or testicular tissue can also be used in patients prior to cytotoxic therapy for non malignant conditions, such as autoimmune diseases, kidney diseases, inflammatory bowel disease and heart transplant procedures. Most of these conditions are not fatal and the patients should be offered freezing of their sperm or testicular tissue prior to the cytotoxic therapy in order to preserve their fertility for the future.

Surgical procedures involving male genitalia:

Sperm freezing can also be used prophylactically before, during, or after certain surgical procedures as these may have serious adverse effects on male genital structure and functions. An example is the varicocele ligation procedure or reconstructive surgery (e.g. vasovasectomy or vasoepididmostomy). Sperm freezing may also be used postoperatively to insure against subsequent loss of patency of the vas deferens

Social and other reasons:

Sperm freezing could be a mean of preserving fertility in men with social reasons to preserve their rights to have children bearing their names, for example soldiers being deployed to combat missions in war. Other reasons for sperm freezing might be immediately pre and postmortem where relatives of a person wish to ensure that the person can have a legal heir.

CONCLUSION:

Applications of sperm freezing now days are diverse and include humans, animals and insects. Despite the undeniable morphological and functional adverse effects that cryopreservation exerts on sperm, it still remains one of the core methods of fertility preservation for patients and healthy volunteer donors. Future studies are expected to concentrate on advancing technology to achieve the goal of “damage free” sperm after freezing. Encouragingly, recent advances in ART suggest that it will be possible eventually to achieve a healthy pregnancy and live birth from freezing of a single sperm or frozen semen sample. Nevertheless, it has proved to be boon in the era of modernization helping childless couples to embrace parenthood. Sperm freezing has become an accepted modality for fertility preservation and childless couples.

If you want to get infertility treatment in Indore in a low budget, then you should come Mohak Infertility Center. We provide IVF, IUI, ICSI, test tube baby, Embryo Donor, Cryopreservation / Sperm / Embryo Freezing etc. services at very low cost in Mohak Infertility Center. We have teams of many experienced ivf doctors. If you are also involved in childless couples, then one must come Mohak Infertility Center Indore. Book an appointment Call now 7898047572 For more information, visit – https://www.mohakivf.com

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To More Post :-  OLIGOSPERMIA : ITS CAUSES SYMPTOMS AND TREATMENT

OLIGOSPERMIA : ITS CAUSES SYMPTOMS AND TREATMENT

Oligospermia is a male fertility issue characterized by a low sperm count. Other aspects of the sexual health of men with this condition are typical. This includes the ability to get and maintain an erection, as well as produce ejaculation at orgasm.

Sperm count in your ejaculate can vary throughout your life. A healthy sperm amount is often necessary for fertility. The World Health Organization (WHO) classifies sperm counts at or above 15 million sperm per milliliter (mL) of semen as average. Anything below that is considered low and is diagnosed as oligospermia.

  • Mild oligospermia is 10 to 15 million sperm/mL.
  • Moderate oligospermia is considered 5 to 10 million sperm/mL.
  • Severe oligospermia is diagnosed when sperm counts fall between 0 and 5 million sperm/mL.
  • Some men with oligospermia can still conceive despite lower sperm counts. Fertilization may be more difficult, however. It may take more attempts than couples without a fertility issue.
  • Other men with oligospermia may have no problem with conception, despite the low sperm numbers.

Some of the most common causes of oligospermia also increase a man’s risk for other fertility issues. This includes sperm motility problems.

Sperm motility refers to how “active” sperm are in a man’s semen. Normal activity allows sperm to swim toward an egg for fertilization easily. Abnormal motility may mean the sperm don’t move enough to reach an egg. The sperm may also move in an unpredictable pattern that would prevent them from reaching an egg.

Causes of Oligospermia

There are many possible causes of oligospermia, including the following:

  • Varicocele – a swelling of the veins that drain the testicle
  • Infection that interferes with sperm production or sperm health
  • Ejaculation problems such as retrograde ejaculation (ejaculation backward into the bladder)
  • Certain medications (alpha blockers, finasteride, antiandrogens)
  • Genetic conditions (Y chromosome deletions, altered chromosomes)
  • Hormonal imbalance (low testosterone, high prolactin levels)
  • Undescended testicles
  • Medical issues such as multiple sclerosis, diabetes or thyroid disorders
  • Heat exposure (hot tubs, baths, saunas)
  • Recreational drugs (Alcohol, cocaine, marijuana)
  • Anabolic steroid use
  • Chronic stress

How to diagnose a  Oligospermia case

Doctor will take a detailed medical history and perform a general physical examination of your genitalia. He will also order a semen analysis and reproductive hormones that include testosterone, FSH and LH.

Low sperm count can be a biomarker of current and future health. If tests show you have a low sperm count, you should seriously consider undergoing a thorough medical evaluation with a specialist to rule out any underlying health conditions. You should also see your doctor annually to stay on top of your overall health and catch anything troubling early, when it is more easily treated.

Treatment

Oligospermia does not mean you have untreatable infertility. Docotr may recommend one of several approaches to improve semen quality.

Home remedies  

1- Track ovulation
2-Have sex more frequently
3- Don’t use lubricants

Treatment may include:

Surgery. For example, a varicocele can often be surgically corrected or an obstructed vas deferens can be repaired. Prior vasectomies can be reversed. In cases where no sperm are present in the ejaculate, sperm can often be retrieved directly from the testicles or epididymis using sperm retrieval techniques.

  • Treating infections. Antibiotics can cure an infection of the reproductive tract, but this doesn’t always restore fertility.
  • Treatments for sexual intercourse problems. Medication or counseling can help improve fertility in conditions such as erectile dysfunction or premature ejaculation.
  • Hormone treatments and medications. Your doctor might recommend hormone replacement or medications in cases where infertility is caused by high or low levels of certain hormones or problems with the way the body uses hormones.
  • Assisted reproductive technology (ART). ART treatments involve obtaining sperm through normal ejaculation, surgical extraction or from donor individuals, depending on your specific situation and wishes. The sperm are then inserted into the female genital tract, or used for IVF or intracytoplasmic sperm injection.

Mohak Infertility Center Indore is one of the Best infertility treatment hospitals and Test tube baby centers. We offer fertility treatments at the most affordable cost in the shortest possible time with the highest success rate which only the Best IVF center in Indore can provide; that’s why we say that we are Best fertility hospital in Indore. Mohak Infertility Center is one of the leading & low-cost fertility treatment hospitals; we provide infertility specialist treatments or IVF treatment cost in Indore on best IVF packages and offers the lowest IVF price in Indore. The Mohak Infertility Center offers all best high-quality fertility treatment and services like In Vitro fertilisation (IVF), Intra Uterine Insemination (IUI), Intra Cytoplasmic Sperm Injection (ICSI),Egg / Sperm / Embryo Donor, Cryopreservation / Sperm / Embryo Freezing, Laparoscopy & Hysteroscopic, test tube baby and Ultrasound Scan etc. Dr Shilpa Bhandari has Reproductive Medicine specialist of Indore India. With his expertise, He has fulfilled many mothers’ hope including more than 5000+ successful Test Tube Babies till date. He has been rewarded with best IVF specialist in Indore, Madhya Pradesh and all over India because of his quality fertility services. Book an appointment Today Call now 7898047572, 8085-277666 For more information, visit – https://www.mohakivf.com

Request an Appointment / General Inquiry:-  https://www.mohakivf.com/Contact-us.htm

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To More Post :-INFERTILITY AND IT ‘S CAUSES :

INFERTILITY AND IT ‘S CAUSES :

Infertility is defined as the inability to conceive within 12 months. If you are infertile, then you cannot get pregnant naturally and have children Approximately 85% of couples will achieve pregnancy within one year of trying, with the greatest likelihood of conception occurring during the earlier months. Additional 7% of couples will conceive in the second year and the couples who are enable to conceive even after trying this long defined as infertile.

Until recently,  it was usually the women who were assumed to be the origin of any fertility issues. However, recent studies as conducted by the International Committee for Monitoring Assisted Reproductive Technology, World Health Organization, show that nearly 50% of  infertility is related to the reproductive anomalies or disorders in the male.

Mohak Infertility Center is a one of the best infertility treatment hospitals and test tube baby centers in Indore. We provide IVF, IUI, ICSI, test tube baby and Egg Donation at very affortable price. Dr Shilpa Bhandari is an experienced IVF specialist at this hospital. Book an appointment Today Call now 7898047572 For more information, visit - https://www.mohakivf.com

WHAT IS REQUIRED FOR A COUPLE TO BECOME PREGNANT:

In order for a couple to become pregnant, at least four things have to happen:

  • OVULATION -A woman must produce and release a healthy egg from one of her ovaries.This is known as ovulation.
  • FERTILIZATION-A man must produce viable sperm which can successfully fertilize the woman’s egg. This procedure is known as fertilization.
  • TRANSPORTATION-The egg must travel through a fallopian tube toward the uterus.
  • IMPLANTATION-The fertilized egg must attach to the inside of the uterus.

What are the causes of low sperm count or abnormal sperm function in men?

Low sperm count or abnormal sperm function may be caused by:

  • Undescended testicles
  • If there is any Genetic defects/DNA damage
  • When a man is suffering from Diabetes
  • If a man had a Prior bacterial or viral infections such as mumps or adenovirus
  • Had a history of trauma or prior surgeries on the testicles or inguinal region
  • If a person has enlarged veins (varicoceles) in the testes that can increase blood flow and heat, both of which affect the number and shape of the sperm
  • If a man is exposed to chemicals like pesticides, radiation, and chemotherapy
  • If a man is an Alcohol user, marijuana user, and uses tobacco smoke
  • If a man is on Steroid 
  • There is overexposure to heat (such as in saunas and hot tubs)
  • If surgical removal of one of the testicles due to cancer

In addition, there can be problems with the delivery of sperm and subsequent fertilization due to any of the following:

  • Premature ejaculation
  • Damage or injury to the reproductive organs
  • Semen entering the bladder instead of emerging through the penis during orgasm (retrograde ejaculation)
  • Certain genetic diseases (such as cystic fibrosis)

Men who have previously had a vasectomy and wish to father a child have two choices. They either need to have the vasectomy reversed or have sperm retrieved through a surgical procedure as part of assisted reproductive techniques.

What are the causes of infertility in women?

The causes of infertility in women can include many of the following:

Hormonal issues: These can be due to the lack of the necessary synchronized hormonal changes leading to the release of an egg from the ovary.

  • Hormonal issues: These can be due to the lack of the necessary synchronized hormonal changes leading to the release of an egg from the ovary.
  1. Disorders of the thyroid gland: Either too much thyroid hormone or too little thyroid hormone can interfere with the menstrual cycle or cause infertility
  2. Gland disorders: These hormonal disorders may include polycystic ovarian syndrome (PCOS), or problems with the hypothalamus, pituitary gland, adrenal gland (such as Cushing’s syndrome or congenital adrenal hyperplasia)
  • Structural issues: Benign growths (such as polyps and fibroids) in the uterus, blocked fallopian tubes, abnormal anatomy of the cervix or uterus, endometriosis, scar tissue
  1. Fallopian tube damage can include scarring from prior surgery and/or pelvic infections. These include pelvic inflammatory disease (PID). Problems with transportation of the egg(s) can occur due to damaged or blocked fallopian tubes.
  • Diminished ovarian reserve, premature menopause or cessation of ovulation (primary ovarian insufficiency); changes in egg quality or quantity can affect fertility
  • Additional factors:
  1. Poor diet that is lacking in nutrients
  2. Athletic overtraining
  3. Stress
  4. Too much exposure to certain chemicals and toxins (for example, tobacco smoke, alcohol, marijuana, pesticides, radiation, and chemotherapy)
  5. Certain medications (the effect usually is temporary)
  6. Sickle cell disease
  7. Kidney disease
  8. Celiac disease
  9. Diabetes

Women who have had a tubal ligation or an Essure® device (forms of permanent birth control) should speak with a gynecologist about their options.

Mohak Infertility Center Indore, is the best fertility hospital in India. Dr Shilpa Bhandari is one of the highly experienced IVF specialist doctors at this hospital. She is Provide the world class treatment for infertility at very affordable price. If are you searching the best centre for IVF in Indore, come at Mohak Infertility Center Indore, MP. Book an appointment Today Call now 7898047572 For more information, visit – https://www.mohakivf.com

Request an Appointment / General Inquiry:-  https://www.mohakivf.com/Contact-us.htm

Please go through our social media :

like our page to now more about IVF

Facebook :-https://www.facebook.com/MOHAK-IVF-1167147806785287/

Please do follow on Instagram

Instagram :- https://www.instagram.com/mohak_ivf/

To More Post :-Why I am not getting pregnant ?

INFERTILITY AND IT ‘S CAUSES :

Infertility is defined as the inability to conceive within 12 months. If you are infertile, then you cannot get pregnant naturally and have children Approximately 85% of couples will achieve pregnancy within one year of trying, with the greatest likelihood of conception occurring during the earlier months. Additional 7% of couples will conceive in the second year and the couples who are enable to conceive even after trying this long defined as infertile .
Until recently,  it was usually the women who were assumed to be the origin of any fertility issues. However, recent studies as conducted by the International Committee for Monitoring Assisted Reproductive Technology, World Health Organization, show that nearly 50% of  infertility is related to the reproductive anomalies or disorders in the male.

WHAT IS REQUIRED FOR A COUPLE TO BECOME PREGNANT:

In order for a couple to become pregnant, at least four things have to happen:

  • OVULATION -A woman must produce and release a healthy egg from one of her ovaries.This is known as ovulation.
  • FERTILIZATION-A man must produce viable sperm which can successfully fertilize the woman’s egg.  This procedure is known as fertilization.
  • TRANSPORTATION-The egg must travel through a fallopian tube toward the uterus.
  • MPLANTATION-The fertilized egg must attach to the inside of the uterus.

What are the causes of low sperm count or abnormal sperm function in men?

Low sperm count or abnormal sperm function may be caused by:

  • Undescended testicles
  • If there is any Genetic defects/DNA damage
  • When a man is suffering from Diabetes
  • If a man had a Prior bacterial or viral infections such as mumps or adenovirus
  • Had a history of trauma or prior surgeries on the testicles or inguinal region
  • If a person has enlarged veins (varicoceles) in the testes that can increase blood flow and heat, both of which affect the number and shape of the sperm
  • If a man is exposed to chemicals like pesticides, radiation, and chemotherapy
  • If a man is an Alcohol user, marijuana user, and uses tobacco smoke
  • If a man is on Steroid 
  • There is overexposure to heat (such as in saunas and hot tubs)
  • If surgical removal of one of the testicles due to cancer

In addition, there can be problems with the delivery of sperm and subsequent fertilization due to any of the following:

  • Premature ejaculation
  • Damage or injury to the reproductive organs
  • Semen entering the bladder instead of emerging through the penis during orgasm (retrograde ejaculation)
  • Certain genetic diseases (such as cystic fibrosis)

Men who have previously had a vasectomy and wish to father a child have two choices. They either need to have the vasectomy reversed or have sperm retrieved through a surgical procedure as part of assisted reproductive techniques.

What are the causes of infertility in women?

The causes of infertility in women can include many of the following:

  • Hormonal issues: These can be due to the lack of the necessary synchronized hormonal changes leading to the release of an egg from the ovary.
  1. Disorders of the thyroid gland: Either too much thyroid hormone or too little thyroid hormone can interfere with the menstrual cycle or cause infertility
  2. Gland disorders: These hormonal disorders may include polycystic ovarian syndrome (PCOS), or problems with the hypothalamus, pituitary gland, adrenal gland (such as Cushing’s syndrome or congenital adrenal hyperplasia)
  • Structural issues: Benign growths (such as polyps and fibroids) in the uterus, blocked fallopian tubes, abnormal anatomy of the cervix or uterus, endometriosis, scar tissue
  1. Fallopian tube damage can include scarring from prior surgery and/or pelvic infections. These include pelvic inflammatory disease (PID). Problems with transportation of the egg(s) can occur due to damaged or blocked fallopian tubes.
  • Diminished ovarian reserve, premature menopause or cessation of ovulation (primary ovarian insufficiency); changes in egg quality or quantity can affect fertility
  • Additional factors:
  1. Poor diet that is lacking in nutrients
  2. Athletic overtraining
  3. Stress
  4. Too much exposure to certain chemicals and toxins (for example, tobacco smoke, alcohol, marijuana, pesticides, radiation, and chemotherapy)
  5. Certain medications (the effect usually is temporary)
  6. Sickle cell disease
  7. Kidney disease
  8. Celiac disease
  9. Diabetes

Women who have had a tubal ligation or an Essure® device (forms of permanent birth control) should speak with a gynecologist about their options.

Mohak Infertility Center is a one of the best IVF centers in Indore. If you are looking for the Best fertility hospital in India, so come at  Mohak Infertility Center Indore, because Our Best infertility hospital in Indore Which Will Help You Make Your Dream Come Alive. Book an appointment Today Call now 7898047572 For more information, visit – https://www.mohakivf.com

Request an Appointment / General Inquiry:-  https://www.mohakivf.com/Contact-us.htm

Please go through our social media :

like our page to now more about IVF

Facebook :-https://www.facebook.com/MOHAK-IVF-1167147806785287/

Please do follow on Instagram

Instagram :-https://www.instagram.com/mohak_ivf/

To More Post :-  In vitro fertilisation (IVF)