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Maternityis the perfect concoction of love, care , nervousness; a completely different yet precious experience for any woman. A woman gets her rebirth with her child. For some women living this moment turn impossible due to infertility. Infertility refers to a condition when the female cannot conceive even after frequent and regular intercourse for an year or more due to any phys2iological or pathological conditions. It is a condition that disturbs the physical, mental and social state of a woman. The cause of infertility may lie in males too, but here we will mention about the infertility in females.

Most of the infertility causes are treatable and can be treated with medications or surgeries and in severe cases where the conservative and surgical approaches don’t work there comes the technology and assistive reproductive techniques. To land to the treatment approach detection of infertility and is cause is most important. 

Here Are The Symptoms That Would Alarm You About Infertility:

• Absent Menstrual Cycle
• Too early (<21 days) or too late (>35 days) menstrual cycle or the excessive painful menstrual cycle
• Multiple miscarriage

What Can Cause Infertility In females?

• Hormonal Imbalances: Pregnancy in humans is a hormone mediated process. Starting from ova maturation to ovulation and preparing the uterus for conceiving and even the abortion is mediated by hormones. Any imbalance in the gonadal hormones involving the oestrogen, progesterone, follicle stimulating hormone, oxytocin may lead to infertility. 
• Ovulation Disorders: Ovulation isthe process of release of mature ova from female ovary. The ovulation disorders are most common cause of infertility:

1. Polycystic Ovary Syndrome
2. Hypothalamic Dysfunction 
3. Premature Ovarian Failure
4. Hyperprolactinemia 

• Tubal Involvement: Damage to fallopian tubes or it’s blockagecan cause infertility , as it is the passage where ova and sperm fuse to form zygote

1. Fallopian tube may be too narrow to allow entry of sperm or egg.
2. Any infection in fallopian tube
3. Any surgical trauma or previous ectopic pregnancy leading to rupture of membrane. 
4. Pelvic Inflammatory Diseases
5. Pelvic Tuberculosis

• Uterus Involvement : Uterus is the major reproductive organ that provides the growing environment to the foetus. Any structural or pathological  condition of uterus may lead to infertility. 

1. Fibroids and uterine tumour 
2. Endometriosis
3. Congenital conditions

• Cervical Involvement: Block in cervix or vagina or any infection that lead to sperm death. The quality of mucous in cervix would affect the entry of sperm. Cervical cancer is a leading cause of infertility in female. Cervical stenosis is another such cause of infertility in female.

What adds the risk ?

• Any abusive substance be it alcohol or any other drugs.
• Smoking or environmental hazards.
• Overweight can lead to hormonal imbalance. 
• Sexually transmitted diseases like HIV, chlamydial infection and gonorrhoea due to previous unprotected sex.
• Overage women , after mid 30’s face more issues due to decrease in follicle maturation rate and improper maturation.

Infertility is a condition that affect the family along with the parents emotionally and mentally, thus with improved technology and secured guidance, live the moments of parenthood. 

If are you suffering from infertility and searching the best IVF specialist in Indore, come to the Mohak Infertility Center, Indore.  Mohak Infertility Center is India’s leading chain of fertility centers, providing world-class Infertility treatment in Indore. We believe in evidence-based treatment and transparency in all interactions with patients. We have a team of very experienced IVF doctors, who have been providing IVF treatment at a very low cost in Indore for many years. We have brought in the world’s most advanced technology, ensuring that all our services are cost-effective. Book an  appointment today with the Best fertility hospital in India, call now us 78980 – 47572 / 80852 -77666 for more information.

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What is PCOS?

Most women with PCOS grow a number of small cysts, or fluid-filled sacs, on their ovaries. The cysts are not harmful, but they can lead to an imbalance in hormone levels.

Women with PCOS may also experience menstrual cycle abnormalities, increased androgen (sex hormone) levels, excess hair growth, acne, and obesity.

In addition to the many health conditions associated with PCOS, which will be discussed in this article, PCOS is the most common cause of infertility in women – because it can prevent ovulation.

Women who can conceive with PCOS have a higher incidence of miscarriage, gestational diabetes, pregnancy-induced high blood pressure, preeclampsia, and premature delivery.

Causes

Currently, there is no known cause of PCOS. However, there are associations with excess insulin, low-grade inflammation, and genetics.

Symptoms

Apart from cysts on the ovaries, symptoms of PCOS include:

• irregular menses
• excess androgen levels
• sleep apnea
• high stress levels
• high blood pressure
• skin tags
• infertility
• acne, oily skin, and dandruff
• high cholesterol and triglycerides
• acanthosis nigricans, or dark patches of skin
• fatigue
• female pattern balding
• insulin resistance
• type 2 diabetes
• pelvic pain
• depression and anxiety
• weight management difficulties including weight gain or difficulty losing weight
• excessive facial and body hair growth, known as hirsutism
• decreased libido

Tests and diagnosis

No single test can determine the presence of PCOS, but a doctor can diagnose the condition through medical history, a physical exam that includes a pelvic exam, and blood tests to measure hormone, cholesterol, and glucose levels.

An ultrasound may be used to look at the uterus and ovaries.

Treatment

There is no cure for PCOS, but treatment aims to manage the symptoms that affect an individual.

This will depend on whether the individual wants to become pregnant and aims to reduce the risk of secondary medical conditions, such as heart disease and diabetes.

There are several recommended treatment options, including:

Birth control pills: These can help regulate hormones and menstruation.

Diabetes medications: These help manage diabetes, if necessary.

Fertility medications: If pregnancy is desired, these include the use of clomiphene (Clomid), a combination of clomiphene and metformin, or injectable gonadotropins, such as follicle-stimulating hormone (FSH) and luteinizing hormone (LH) medications. In certain situations, letrozole (Femara) may be recommended.

Fertility treatments: These include in-vitro fertilization (IVF) or inseminations.

Excessive hair growth may be reduced with the drug spironolactone (Aldactone) or eflornithine (Vaniqa). Finasteride (Propecia) may also be recommended, but it should not be handled by women who may become pregnant.

Anyone using spironolactone should use birth control, due to the risk of birth defects if taken while pregnant. Breast-feeding on this medication is not recommended.

Other possible options to manage hair growth is laser hair removal, electrolysis, hormonal treatments, or vitamin and mineral use.

Surgical options include:

Ovarian drilling: Tiny holes made in the ovaries can reduce the levels of androgens being produced.
Oophorectomy: Surgery removes one or both ovaries.
Hysterectomy: This involves removal of all or part of the uterus.
Cyst aspiration: Fluid is removed from the cyst.

Pregnancy and menopause

Women who are affected by PCOS may experience the effects throughout their lifetime.

There may be an increased risk of miscarriage, gestational diabetes, preeclampsia, and preterm births.

After delivery, there is an increased risk of the newborn being placed in the neonatal intensive care unit or death before, during, or soon after birth. These complications are more common in multiple births, for example, twins or triplets.

Symptoms such as excessive hair growth and male pattern baldness can last beyond menopause and may become worse.

With aging also comes the risk of the secondary health complications related to PCOS, including heart disease.

Mohak Infertility Center is the Best centre for IVF in Indore and provides all infertility treatment at very affordable price. If you  are suffering from infertility and searching the best IVF center in Indore, come to the Mohak Infertility Center, because  Mohak Infertility Center is one of the best IVF centers in MP. Book an appointment today call now us 78980- 47572 / 80852-77666 for more information.

Request an Appointment / General Inquiry:- https://www.mohakivf.com/Contact-us.htm

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To More Post :- How does a short luteal phase affect fertility?

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The spontaneous loss of a woman’s pregnancy before the 20th week that can be both physically and emotionally painful.

Miscarriage is the most common type of pregnancy loss and often occurs because the foetus isn’t developing normally. Miscarriage can also be genetically.

Symptoms of miscarriage include:-

Miscarriage are both physically and mentally painful. In some cases female can’t have next pregnancy. Some of the symptoms include:

• cramps
• Abdominal pain
• Bleeding which turn from low to high level
• Weakness which some time cause faint
• Back pain
• Fever
• Abdominal infection
• Urinal problems

Can I get pregnant after miscarriage :

Yes. At least 85% of women who have miscarriages have subsequent normal pregnancies and births. Having a miscarriage does not necessarily mean you have a fertility problem. If you’ve had two miscarriages in a row, you should stop trying to conceive, use a form of birth control , and ask your health care .

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Can a Miscarriage Be Prevented?

Usually a miscarriage cannot be prevented and often occurs because the pregnancy is not normal. If a specific problem is identified with testing, then treatment options may be available. Sometimes,treatment of a mother’s illness can improve the chances for a successful pregnancy. Basically to prevent miscarriage a female should take some basic medicine that helps in building up the baby Or foetus. sure to take at least 400 mg of folic acid every day, beginning at least one to two months before conception, if possible.

• Exercise regularly.
• Eat healthy, well-balanced meals.
• Manage stress.
• Keep your weight within normal limits.
• Don’t smoke and stay away from smoke.
• Don’t drink alcohol
• Avoid illicit drugs.
• Take proper rest
• Make sure you are up to date on immunizations.

If are you searching the Best infertility hospital for Infertility treatment in Indore, come in to the Mohak Infertility Center,  Indore, because we are the Best IVF center in MP. We have an experienced team of IVF specialist doctors, who provide  treatments like IVF, IUI, ICSI, test and tube baby at very low cost. Book an appointment today call now us 78980- 47572 /  80852-77666 for more information.

Request an Appointment / General Inquiry:- https://www.mohakivf.com/Contact-us.htm

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In order to extract and fertilize the eggs during IVF, doctors generally follow the same process everytime. Once fertilization has occurred, there are a few different options available for embryo transfer:

Fresh embryo transfer: Once eggs have been fertilized, they are cultured for 1-2 days. The best embryos are chosen to transfer directly to the woman’s uterus.

Frozen embryo transfer: Any healthy embryos that were not used in the first transfer can be frozen and stored for future use. These can be thawed and transferred to the uterus.

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Blastocyst embryo transfer: If many healthy embryos develop after the fertilization, it is common to wait to see if the embryos develop into blastocysts. According to a study in the Indian Journal of Clinical Practice, blastocyst embryo transfer has a higher success rate than the standard embryo transfer on day 3. However, another recent study suggests that it may pose risks later in pregnancy and should not always be recommended.

Assisted hatching (AH): A study in the Reproductive Biomedicine Online found that the process of assisted hatching – weakening the outer layer of the embryo before it is transferred to the uterus – does not improve pregnancy and implantation rates in women who are having fresh embryos transferred. The researchers noted, however, that women having frozen embryos implanted do benefit from having their embryos treated in this way.

Mohak Infertility Center is the Best infertility hospital in Indore. We provide IVF treatment, test tube baby treatment and ICSI treatment in Indore at very low cost, If are you want IVF treatment with best IVF center in Indore, visit at the Mohak Infertility Center. Book an appointment Today call us 7898047572 and  ivf related for more information.

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There’s no cure for endometriosis. Treatments usually include surgery or medication. You might need to try different treatments to find what helps you feel better.

Pain medicine. Your doctor may recommend an over-the-counter pain reliever. Non-steroidal anti-inflammatory drugs (NSAIDs) like ibuprofen (Advil, Motrin) or naproxen (Aleve) work for many people. If these don’t relieve your pain, ask about other options.

Some other things you can do at home may help with pain:

• Take warm baths.
• Put a hot water bottle or heating pad on your belly.
• Exercise regularly.

Some women find that alternative therapies like acupuncture, diet changes, or homeopathy work for them. Before starting one, talk to your doctor to be sure it won’t interfere with another treatment.

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Hormones. Hormonal therapy lowers the amount of estrogen your body creates and can stop your period. This helps lesions bleed less so you don’t have as much inflammation, scarring, and cyst formation. Common hormones include:

• Birth control pills, patches, and vaginal rings
• Gonadotropin-releasing hormone (Gn-RH) agonists and antagonists such as elagolix sodium (Orilissa) or leuprolide (Lupron)
• Progestin-only contraceptives
• Danazol (Danocrine)

Surgery. Your doctor might recommend surgery to take out as much of the affected tissue as possible. In some cases, surgery helps symptoms and can make you more likely to get pregnant. Your doctor might use a laparoscope or do a standard surgery that uses larger cuts. Pain sometimes comes back after surgery.

In the most severe cases, you may need a surgery called a hysterectomy to take out your ovaries, uterus, and cervix. But without them, you can’t get pregnant later.

Are you planning for Infertility treatment in Indore? If your answer is yes, so come in Mohak Infertility Center Indore because,  Mohak Infertility Centers is one of the best IVF centers in Indore. We provide IVF, IUI, ICSI, test tube baby, infertility treatment and other IVF related treatment very affordable price. Dr. Shilpa Bhandari is highly experienced IVF specialist doctor of this hospital.  Book an appointment today with the best IVF specialist in Indore call now us 7898047572 and online visit https://www.mohakivf.com/ for more information.

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Infertility refers to the condition in which a female not getting pregnant, although by having carefully timed, unprotected sex for one year.

The cause of infertility may be difficult to determine but may include inadequate levels of certain hormones in both men and women, and trouble with ovulation in women. Smoking, alcohol and drug are the major problem of infertility in both male and female. The effects of smoking on male reproductive part (sperm) and female reproductive part (ovum) are affected.

Effect of smoking on MALE :

Sperm concentration: Sperm concentration refers to the number of sperm found in a measured quantity of semen. Studies have shown a 23 percent decrease in sperm concentration in men who smoke.

Sperm motility: Sperm motility refers to the swimming capabilities of the sperm. If sperm cannot swim properly, they may have trouble reaching the egg and fertilizing it.

Sperm morphology: Sperm morphology refers to the shape of sperm. Oddly shaped sperm may not swim well enough to get to the egg and may not be able to fertilize an egg. Male smokers have fewer healthy shaped sperm than non-smokers.

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Harmful toxins are found in cigarettes are frequently to blame for bad health effects. Smoking exposes men to high levels of cadmium that have been linked to decreased fertility. Heavy smoker were found to have higher levels of cadmium in their semen.

But these toxins may not be the only factor. Zinc levels may play a role. Male smokers who had lower zinc levels in their semen also had poor sperm concentration, movement, and shape.

On the other hand, in smokers who had normal semen zinc levels, there were still issues with sperm concentration, motility, and morphology, but the degree of abnormality was less.

Effect of smoking on FEMALE :-

Women who smoke do not conceive as efficiently as non-smokers. The risk for fertility problems increases with the number of cigarettes smoked daily.

Even fertility treatments such as IVF may not be able to fully overcome smoking’s effects on fertility. Female smokers need more ovary-stimulating medications during IVF

Smoking damages the genetic material in eggs and sperm, miscarriage and offspring birth- defect rates are higher among patients who smoke. Smokeless tobacco ,drugs, drinks, alcohol and other harmful products also leads to increased miscarriage rates. Women who smoke are more likely to conceive a chromosomally unhealthy pregnancy than non-smoking mothers. Ectopic pregnancies also occur more often among female smokers.

If are you looking the best IVF center in MP? if yes, so visit in Mohak Infertility Center Indore, because Mohak Infertility Center is one of the best fertility hospitals in India. This hospital provide the best infertility treatment and ICSI treatment in Indore at very affordable price. Dr Shilpa Bhandari is many years  experienced ivf specialist in Mohak Infertility Center. Dr Shilpa Bhandari is an ardent believer in open patient communication, maintaining and honest doctor patient relationship and patient empowerment. Her dream is to provide affordable, honest patient care to couple seeking to enhance their families. If you are suffering  from infertility so Book an appointment with best IVF center in Indore call now us 7898047572.

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Semen freezing is the procedure whereby spermatozoa are exposed to cryoprotectants and then cooling them to subzero temperature using liquid nitrogen. Frozen semen samples can be stored for many years while maintaining reasonable parameters of semen. Semen freezing helps in storage, supply or reserve of the human sperm for future use.

Sperm freezing is widely used and established method in humans and other species, it is very effective in Assisted Reproductive technology (ART) and fertility preservation in patients with cancer, before initiation of radiotherapy or chemotherapy. Semen freezing can be done by two methods 1. Noncontrolled rate cryopreservation and 2. Controlled rate cryopreservation.

CLINICAL APPLICATION OF SPERM FREEZING :-

1.Assisted Reproductive Technologies (ART)

2. Fertility Preservation with Cancer Therapy

3. Non- malignancy systemic diseases and other conditions

4. Surgical procedures involving male genitalia

5. Social and other reasons

ART – Assisted reproductive technologies – IUI/IVF/ICSI:

In ART, the most common use of sperm freezing is in artificial insemination, in vitro fertilization (IVF), or intra cytoplasmic sperm injections (ICSI) for various infertile couples. One of the ART options usually offered to infertile couples is intrauterine insemination using fresh or frozen sperm. Although the technique is used preferably with a fresh semen sample, the availability of freezing sperm samples is an option usually offered by infertility clinics in case the male partner cannot produce semen. In case of severe male factor infertility, the samples can be frozen for later use.

Fertility Preservation with Cancer Therapy:

Another application of sperm freezing is for cancer patients before initiation of cancer therapy. The option of sperm freezing should be offered to any male undergoing chemotherapy or radiotherapy as these treatments can have long-term or permanent cytotoxic side effects on testicular function. One of the advantages of semen freezing is here is that the frozen sperm can stand multiple freezing thawing cycles with no effect on the sperm quality; this is beneficial in cases where patients might have testicular cancer and require surgical removal of the whole testis, with no future possibility of obtaining sperm again. For young males before puberty , cryopreservation of testicular tissue may be an option for fertility preservation in future, improved chemotherapy regimens may give hope to patients in terms of maintaining their sexual and fertility potential after therapy, but at present all male patients diagnosed with cancer who wish to have children should consider sperm freezing or cryopreservation of testicular tissues for further ART use.

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Non- malignancy systemic diseases and other conditions:

Cryopreservation of sperm or testicular tissue can also be used in patients prior to cytotoxic therapy for non malignant conditions, such as autoimmune diseases, kidney diseases, inflammatory bowel disease and heart transplant procedures. Most of these conditions are not fatal and the patients should be offered freezing of their sperm or testicular tissue prior to the cytotoxic therapy in order to preserve their fertility for the future.

Surgical procedures involving male genitalia:

Sperm freezing can also be used prophylactically before, during, or after certain surgical procedures as these may have serious adverse effects on male genital structure and functions. An example is the varicocele ligation procedure or reconstructive surgery (e.g. vasovasectomy or vasoepididmostomy). Sperm freezing may also be used postoperatively to insure against subsequent loss of patency of the vas deferens

Social and other reasons:

Sperm freezing could be a mean of preserving fertility in men with social reasons to preserve their rights to have children bearing their names, for example soldiers being deployed to combat missions in war. Other reasons for sperm freezing might be immediately pre and postmortem where relatives of a person wish to ensure that the person can have a legal heir.

CONCLUSION:

Applications of sperm freezing now days are diverse and include humans, animals and insects. Despite the undeniable morphological and functional adverse effects that cryopreservation exerts on sperm, it still remains one of the core methods of fertility preservation for patients and healthy volunteer donors. Future studies are expected to concentrate on advancing technology to achieve the goal of “damage free” sperm after freezing. Encouragingly, recent advances in ART suggest that it will be possible eventually to achieve a healthy pregnancy and live birth from freezing of a single sperm or frozen semen sample. Nevertheless, it has proved to be boon in the era of modernization helping childless couples to embrace parenthood. Sperm freezing has become an accepted modality for fertility preservation and childless couples.

If you want to get infertility treatment in Indore in a low budget, then you should come Mohak Infertility Center. We provide IVF, IUI, ICSI, test tube baby, Embryo Donor, Cryopreservation / Sperm / Embryo Freezing etc. services at very low cost in Mohak Infertility Center. We have teams of many experienced ivf doctors. If you are also involved in childless couples, then one must come Mohak Infertility Center Indore. Book an appointment Call now 7898047572 For more information, visit – https://www.mohakivf.com

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To More Post :-  OLIGOSPERMIA : ITS CAUSES SYMPTOMS AND TREATMENT